Spicy Southern Cheesy Chicken Spaghetti Casserole Recipe

If you’re craving a dish that’s bursting with bold flavors and creamy textures, the Spicy Southern Cheesy Chicken Spaghetti Casserole is exactly what you need. This hearty casserole perfectly combines tender chicken, al dente spaghetti, sharp cheddar cheese, and a spicy Southern kick to create a cozy meal that’s both comforting and exciting on the palate. Whether you’re serving family or guests, this dish has that irresistible cheesy zing and a touch of heat that will have everyone asking for seconds.

Ingredients You’ll Need

These ingredients are straightforward and beloved in Southern cookery, each adding its own essential touch to the Spicy Southern Cheesy Chicken Spaghetti Casserole. From the creamy chicken soup that bonds everything together, to the vibrant bell peppers that add color and crunch, every element plays a starring role in delivering the perfect balance of taste and texture.

• 3-4 boneless, skinless chicken breasts (about 1.5 lbs): The protein base that brings juiciness and substance to the casserole.
• 8 oz spaghetti: Offers a great carb foundation that soaks up all those delicious flavors.
• 2 cups shredded sharp cheddar cheese: Adds a rich and tangy cheesiness that melts beautifully over the casserole.
• 1 cup fresh bell peppers (chopped): Gives a sweet, crisp contrast and bursts of color.
• 1 can (10.5 oz) cream of chicken soup: The secret creamy binder that keeps everything luscious and moist.
• 1 tsp paprika: Brings smoky warmth and a mild spice depth.
• 1/2 tsp cayenne pepper: Delivers the signature Southern kick that makes this dish unforgettable.
• 1 tsp garlic powder: Adds savory undertones without overpowering the other spices.
• 1/4 cup green onions (sliced): Perfect for garnishing, adding freshness and a slight sharpness.

How to Make Spicy Southern Cheesy Chicken Spaghetti Casserole

Step 1: Preheat and Prepare

Start by preheating your oven to 350°F (175°C) and generously grease a large casserole dish. This ensures your cheesy, spicy spaghetti casserole won’t stick and will bake evenly to that golden perfection we all crave.

Step 2: Cook the Chicken

In a large pot over medium heat, cook the chicken breasts for about 6 to 7 minutes per side until they develop a beautiful golden crust and are cooked through. This step guarantees tender, juicy chicken that’ll shred easily and soak up all those great spices.

Step 3: Boil the Spaghetti

While the chicken cooks, boil salted water and cook the spaghetti according to package instructions—aiming for al dente, about 8 to 10 minutes. Make sure to drain it well, so it blends perfectly without becoming mushy in the casserole.

Step 4: Mix the Magic

Once the chicken is cooked, shred it into bite-sized pieces. In a large bowl, combine shredded chicken, cooked spaghetti, cream of chicken soup, chopped bell peppers, paprika, cayenne pepper, garlic powder, and half the shredded cheddar cheese. This mixture packs the heat, creaminess, and flavorful texture that make this recipe such a standout.

Step 5: Assemble and Bake

Transfer your cheesy chicken spaghetti mixture into the greased casserole dish and evenly sprinkle the remaining cheddar cheese on top. Pop it in the oven and bake for 25 to 30 minutes until the cheese is melted, bubbly, and delightfully golden brown on top.

Step 6: Rest and Garnish

Once out of the oven, let your Spicy Southern Cheesy Chicken Spaghetti Casserole rest for about five minutes. This little pause helps it set perfectly. Then sprinkle the sliced green onions on top for a fresh, zesty finish before serving.

How to Serve Spicy Southern Cheesy Chicken Spaghetti Casserole

Garnishes

A sprinkle of freshly chopped green onions is classic, adding a subtle onion tang and a pop of color. For an extra Southern touch, try adding crushed red pepper flakes or a dollop of sour cream to balance the heat and elevate the creaminess further.

Side Dishes

This casserole pairs beautifully with simple sides like a crisp green salad dressed lightly with vinaigrette or a side of buttery cornbread to soak up any extra cheesy sauce. Steamed green beans or roasted vegetables can also add a fresh, nutritious contrast to the indulgent casserole.

Creative Ways to Present

For a fun twist, serve the casserole in individual ramekins for a pretty plated look or scoop portions into bell pepper halves for a colorful, Southern-inspired presentation. You could also layer the casserole with extra cheese or jalapeño slices for an eye-catching, spicier version.

Make Ahead and Storage

Storing Leftovers

Store any leftover Spicy Southern Cheesy Chicken Spaghetti Casserole in an airtight container in the refrigerator for up to 3 to 4 days. This allows the flavors to deepen, and reheating it later is just as tasty as the first serving.

Freezing

This casserole freezes wonderfully. Place portions in freezer-safe containers or wrap the entire dish in foil and plastic wrap. Freeze for up to 2 months for a ready-to-bake comfort meal on a busy day.

Reheating

Reheat leftovers in the oven at 350°F (175°C) until warmed through and bubbly, about 20 minutes. Microwaving works too—just cover loosely and heat in short bursts to keep it creamy and prevent drying out.

FAQs

Can I use a different type of pasta?

Absolutely! While spaghetti is traditional for this recipe, you can substitute elbow macaroni, penne, or even rotini to add some different texture and catch more sauce.

How spicy is the casserole?

The heat level is moderate, thanks to the cayenne pepper, but you can adjust it to your liking by adding more or less cayenne or even diced jalapeños for extra fire.

Is this recipe suitable for meal prep?

Yes, it’s perfect for meal prep. Prepare it in advance, refrigerate or freeze, then bake when you’re ready to enjoy a quick, satisfying meal.

Can I use leftover cooked chicken?

Definitely! Using leftover chicken works great and can actually save you some cooking time, making the recipe even easier to pull together.

What if I want it less creamy?

Reduce the cream of chicken soup slightly and add a splash of chicken broth instead. This will lighten the casserole while still keeping it flavorful and moist.

Final Thoughts

I cannot recommend enough giving this Spicy Southern Cheesy Chicken Spaghetti Casserole a spot on your dinner table. Its perfect blend of cheesy richness, just-the-right amount of heat, and Southern comfort is downright irresistible. Trust me, once you try this recipe, it’ll become a treasured go-to for cozy family meals and special occasions alike.

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